Evaluation of mosquito larvicidal effect of carica papaya against aedes aegypti p. Sensitivity, clinical isolates, urinary tract, carica papaya, extract, fractions introduction medicinal plants are cheap and renewable sources of pharmacologicallyactive substances and are known to produce certain chemicals that are naturally toxic to bacteria basile et al. Nutraceutical potential of carica papaya in metabolic syndrome. Leaves contain large amounts of alkaloids, carpaine and pseudocarpine which creates. Using controlled in vivo and in vitro pharmacological methods, we evaluated the safety of papaya carica papaya consumption in pregnancy with reference to its common avoidance during pregnancy in some parts of asia.
It has been documented in literature for its use by natives of various parts of world and also for its antiinflammatory. Seven to eight longitudinal incisions were made in order to allow latex to appear and drain in the collecting devices. Sarcotesta showed higher percentages of ash, crude protein, and crude fiber than did endosperm, but was lacking in fat. The highland papayas, vasconcellea, are considered the nearest relatives to carica papaya although the relationship is not close aradhya et al. This consensus document addresses compositional considerations for new varieties of papaya carica papaya l. Carica is a genus of flowering plants in the family caricaceae including c. Consequently, the resulting nonwatersoluble material is generally considered as waste, and in comparison to the water soluble fraction, little is known regarding its chemical composition 15. Lako, 2007nd egcg persea americana hydromethanolic seed calderonoliver et al. Biochemical properties in peel, pulp and seeds of c. The pharmacokinetic properties of hiv1 protease inhibitors. Since, each part of papaya tree possesses economic value, it is grown on commercial scale. Review on nutritional, medicinal and pharmacological. Carica papaya, aerial parts, anticancer activity, phytoconstituents.
Chemical profile of unripe pulp of carica papaya pakistan journal of nutrition 4 6. Carica papaya is an evergreen shrub or small tree that. Pawpaw carica papaya belongs to the family caricaceae with over twenty species but only one member of the genus carica is cultivated as a fruit tree, while the other three genera cyclicomorpha, jarilla and jacaratia are grown primarily as ornamentals. Carica papaya methanolic, hexane, ethanol, ethylacetate,dichloromethane. This has necessitated the need for a research and development of ecofriendly. Chemical composition of various part of carica papaya plant are described table 5. The leaves and fruits of five carica papaya morphotypes were harvested from trees in home gardens in umu ahia, abia state, nigeria. Chemical constituents and nutrient composition of carica. Chemical constituents and nutrient composition of carica papaya and vernonia amygdalina leaf extracts. Phytochemical screening and evaluation of platelet. Cytotoxicity of the carica papaya aerial parts extracts was carried out by using mtt colormetric methods. Phytochemical examination of the leaves of carica papaya l. Fresh leaves samples of the plant were collected during the month of january, 20 from different parts of bhuj in kachchh district gujarat, india.
Chemical composition of leaves, fruit pulp and seeds in some carica papaya l morphotypes article pdf available january 2012 with,854 reads how we measure reads. Phytochemical screening of the polar extracts of carica. Phytochemical screening, antimicrobial and antioxidant. These active principles or ingredients occur naturally in such plants bamisaye, et al. Pdf biochemical constituents in leaf of carica papaya. As a dual or multipurpose, earlybearing, spaceconserving, herbaceous crop, it is widely acclaimed, despite its susceptibility to natural enemies. Qualitative chemical analysis of juice carica papaya shown in table1, which indicated that juice contents were. Pdf on jan 10, 2017, okpe oche and others published chemical constituents and nutrient composition of carica papaya and vernonia amygdalina leaf extracts find, read and cite all the research. The high level of natural self defence compounds in the tree makes it highly resistant to insect and disease infestation 9. Amongst such medicinal plants is pawpaw carica papaya. Seeds were extracted from the fruits and the pro ximate, mineral and vitamin analysis carried out on the leaves, fruit s and. Pdf the leaves and fruits of five carica papaya morphotypes were harvested from trees in home gardens.
Chemical composition of leaves, fruit pulp and seeds in some carica papaya l morphotypes. Other studies showed that carica papaya fruit is a source of good componentsmany like. Caricaecae blend 500 mll water was freely given to four groups of spraguedawley rats at different stages of gestation days 15, 611, 12. Chemical composition of papaya carica papaya seeds. Evaluation of carica papaya leaf extracts for their. Chemical composition of various parts of carica papaya. This work describes biochemical constituents of leaves of c. The medicinal properties of papaya fruit and other parts of the plant are also well known in traditional system of medicine. The standard method of analysis used was able to identify really that carica papaya. Some chemical compounds occurring in carica papaya. A general description of these components is provided. Platelets are the type of blood cells produced from megakaryocytes by the action of a major hormone thrombopoietin. The alkaloid, carpaine, was isolated and identified. Medicinal uses of carica papaya anitha b2, raghu n1, gopenath ts3.
Oil extract showed very high levels of oleic and palmitic acids. Its origin is in the tropics of the americas, perhaps from central america and southern mexico. Under greenhouse conditions plants treatments with c. Phytochemical and antioxidant nutrient constituents of carica. The morphotypes were based on fruit shape and pulp colour and are oblong red, oblong yellow, pear orange, round orange and round yellow. Veteran, malang 65145, jawa timur province, indonesia. Carica papaya contains an enzyme known as papain which is present in the bark, leaves and fruit. Pdf chemical constituents and nutrient composition of. Carica papaya is a fast growing, softwooded, herbaceous plant reaching 310 m in height. Selected studies on pharmaceutical application of carica papaya on laboratory animals the effects of carica papaya on laboratory animals have been. Chemical composition of various parts of carica papaya linn. Carica papaya is an herbaceous plant belonging to the family caricaceae.
Cambridge university today to help victims of strokes, heart diseases and press. The basic constituents of the leaves of carica papaya. Vasugi abstract the development of resistance to chemical insecticides among mosquito species has been considered as a setback in vector control. There were animal studies suggest that papaya leaf extracts have potential therapeutic effect on disease.
Biochemical constituents in leaf of carica papaya ethnomedicinal plant of kachchh region article pdf available march 2014 with 5,380 reads how we measure reads. Phytochemical and antioxidant nutrient constituents of. The seed is a rich source of proteins 278% undefatted, 444% defatted, lipids 283% undefatted and crude fibre 226% undefatted, 318% defatted. The leaves are large 3060 cm long, yellowgreen to darkgreen in colour, palmatelylobed, arranged spirally and clustered at the crown. Ogant department of biochemistry, division of biological sciences, university of nigeria, nsukka, nigeria received 15 december 1970 abstractthe alkaloid caxpaine has been isolated from the leaves of the. Anjana gv, priya d, srimathi r, shantha kumar b department of pharmaceutical chemistry, srm college of pharmacy, srm institute of science and technology, chennai, tamil nadu, india.
Additional sources and suggested readings 1 papaya wikipedia, the free encyclopedia 2 chemical profile of unripe pulp of carica papaya pakistan journal of nutrition 4 6. Phytoconstituents were isolated by the treating with naoh and hcl, and further get separated by column chromatography. Chemical composition of leaves, fruit pulp and seeds in. Carica papaya article about carica papaya by the free. Evaluation of mosquito larvicidal effect of carica coden. Pdf phytochemical and antioxidant nutrient constituents. Carica papaya leaf decoction, an australian aboriginal remedy, has been used widely for its healing capabilities against cancer, with numerous anecdotal reports. Okpe oche 1, attah rosemary 1, ojowu john 1, edenta chidi 2, samuel m. The chemical constituents were analysed using gas chromatography mass spectrometry gcms. Drying methods had significant p of the seeds, with freezedrying. K7g carica papaya ethanolic, aqueous fruit pulp, dry leaf kongkachuichai and charoensiri, 2010. Effect of drying methods on the phytochemicals composition. Phytochemical screening and hypoglycemic activity of carica.
The results suggest that petroleum ether extract of c. Green synthesis of silver nanoparticles using carica papaya. Leaves ethyl acetate extract to african catfishclarias gariepinus leucocytes using uvvis, ftir and gcms methods dyah setyawati1,2, sri andayani1, uun yanuhar1 1department of aquaculture, faculty of fisheries and marine science, universitas brawijaya, jl. Jul 26, 2018 carica papaya is also used in the treatment of ulcers, 7 diabetics, 8 etc. The results in table 2 and 3 showed that carica papaya extracts were minimal toxic and showed antihiv1 activity. Role of carica papaya leaf extract for dengue associated. Chemical composition of leaves, fruit pulp and seeds in some. The objective of the present investigation was to study the chemical composition of leaves of carica papaya belonging to family caricaceae growing in semiarid region of kachchh district, gujarat. Papaya leaves have been used in the treatment of various ailments 2. Journal of complementary and alternative medical research, issn. Seeds are antiparasite and can be ground and used like black pepper. Traditional aboriginal preparation alters the chemical. Jun 05, 2012 the carica papaya extract cpe have hepatoprotective effect against carbon tetrachloride intoxicated rats and it may be mediating its protective effects either by decreasing the metabolic activation of carbon tetrachloride, or by acting as a chainbreaking antioxidant for scavenging free radicals or by a combination of these effects.
Carica papaya, also called as pawpaw is traditionally cultivated for fruit. Seeds of papaya cultivated in somalia, which accounted for about 16% of the fresh fruit weight, were divided into sarcotesta and endosperm. In reference to the phytochemical analysis of carica papaya l. International journal of current microbiology and applied sciences. Carica papaya leaves extracts for the treatment of dengue fever. This work describes biochemical constituents of leaves of carica papaya. Drying methods had significant p free binding energy analysis for antiviral activities identi. The hypoglycemic activities of carica papaya have been previously described for its fruit and leaves aruoma et al. This document provides an overview of baseline biological information relevant to risk assessment of genetically modified forms of the species that may be released into the australian environment. The leaves of this plant were collected from pune area, dried, powered and then extracted with ethanol. The seed is a rich source of proteins 278% undefatted, 444% defatted, lipids 283% undefatted and. Defatted and undefatted seeds of papaya carica papaya were analyzed for proximate composition, some toxicants, sugar composition, mineral content, physico chemical properties of the seed oil and the fatty acid spectrum of the seed oil. Caricaceae for possible antioxidant phytochemicals, proximate nutrient constituents, amino acid composition and mineral content present in the samples using standard chemical and chromatographic procedures. Pdf chemical composition of leaves, fruit pulp and seeds.
Defatted and undefatted seeds of papaya carica papaya were analyzed for proximate composition, some toxicants, sugar composition, mineral content, physicochemical properties of the seed oil and the fatty acid spectrum of the seed oil. This study focuses on the latex coming from its fruits of papaya cx variety. A students guide to tho e deadly venoms of some cowrie shells which are used seashore. Phytochemical screening confirmed the presence of folic acid, vitamin b. The therapeutic effects of carica papaya leaves are presumed to be due to several active components such as papain, chymopapain, cystatin, ltocopherol, ascorbic acid, flavonoids, cyanogenic glucosides and glucosinolates. Leaves, fruit and seeds of the carica papaya are used as ethno medicine. Sd on the phytochemicals composition and antioxidant activities of carica papaya seeds, a medicinal plant, was investigated. In this study we investigated its in vitro cytotoxicity on human squamous cell carcinoma cells followed by metabolomic profiling of carica papaya leaf decoction and leaf juicebrewed leaf juice to determine the effects imparted by the. Chemical constituents of cowry cyparica samplomoneta. Routine crude drug assays and tests tor stetoidal saponins, flavonols, tannins, phenols, organic acids, unsaturated sterols and alkaloids have been made on the leaves of carica papaya l. Papaya carica papaya consumption is unsafe in pregnancy. Pdf chemical composition of leaves, fruit pulp and seeds in some. Structural elucidation of mainly two column fractions was carried out using gcms. Anticancer activity of carica papaya extracts in and.
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